

This blend of bio-identical nutrients has been selected with the aim of embracing a maximum benefits.
Cellular health
Health mental
Energy
Key enzyme syntheses
Immune system
Eye health
Digestive health
Fertility
Pregnancy & lactation
Bone health
Acid-base balance
Nutricosmetics
How many capsules?
* Adolescents who may have difficulty swallowing capsules, we recommend that you open them and pour the contents into a glass of water, yogurt or compote.
Precautions for use
For 3 capsules |
Quantity | NRV* | For 3 capsules | Quantité | |
Vitamins | Co-factors | ||||
Vitamin A (from Dunaliela) |
800 μg | 100% | N-Acetyl-Cysteine | 180 mg | |
Vitamin B1 (Thiamine HCL) |
2,2 mg | 200% | Alpha Lipoic Acid (form R) | 50 mg | |
Vitamin B2 (Riboflavin) |
2,8 mg | 200% | Rutin (extract of S. japonica) | 32 mg | |
Vitamin B3 (Nicotinamide) | 16 mg | 100% | Hesperidin (citrus extract) | 32 mg | |
Vitamin B5 (Calcium pantothenate) |
6 mg | 100% | CoEnzyme Q10 | 30 mg | |
Vitamin B6 (Pyridoxal-5-phosphate) |
2 mg | 143% | Quercetin (extract of S. japonica) | 20 mg | |
Vitamin B7 (Inositol) |
30 mg | - | Montein (tagetes extract) | 7 mg | |
Vitamin B8 (Biotin) | 51 μg | 100% | Lycopene (tomato extract) | 1 mg | |
Vitamin B9 (Quatrefolic®) | 200 μg | 100% | |||
Vitamin B12 (Methylcobalamin) | 2,7 μg | 100% | Autres ingrédients | ||
Vitamin C ( L-Ascorbic acid) | 80 mg | 100% | Magnesium sucrosome, Capsule of vegetable origin HPMC, N-acetyl-L-cysteine, Alpha lipoic acid, Nu-RICE®, Zinc gluconate, Ascorbic acid, Dunaliela extract, Menaquinone-7, Rutin, Hesperidin, CoQ10, Inositol, d-alpha-tocopheryl acetate, Quercetine, Nicotinamide, Selenie yeast, Tagetes extract, Lichen cholecalciferol, Rockweed extract, Calcium pantothenate, Tomato extract, Pyridoxal-5-phosphate, Riboflavin, Thiamine HCL, (6S)-5-methyltetrahydrofolic acid, Methylcobalamin, Chromium piccolinate, Biotin. | ||
Vitamine D3 (Cholecalciferol de lichen) | 1000 UI |
500% | |||
Vitamin E (Nutrabiol®) | 12 mg | 100% | |||
Vitamin K2 (K2VITAL® DELTA) | 80 μg | 107% | |||
Minerals | |||||
Magnesium element (UltraMag®) |
150 mg | 40% | |||
Zinc element (Gluconate) | 10 mg | 100% | |||
Selenium (Selenium yeast) | 30 μg | 54% | |||
Iodine (Rockweed extract) | 10 μg | 6,7% | |||
Element chromium (Chromax®) | 25 μg | 62% |
*NRV : nutritional reference values
Vitamins belong to the category of micronutrients (also including minerals and trace elements). The latter are components that derive mainly from our diet because they are not synthesized by our body. Micronutrients are required in small quantities for our vital development, the prevention of pathologies and our general well-being [1]. Every day, our organism needs vitamins for its physiological homeostasis, which are found in our diet. There are two categories of vitamins: water-soluble vitamins, i.e. soluble in water (group B and C vitamins), and fat-soluble vitamins, i.e. soluble in fat (vitamins A, D, E and K).
Vitamin B5 (Pantothenic acid)Mushrooms, liver, eggs, abas, certain poultry and cheese
Vitamins | Food sources* Foods richest in g of vitamin per 100 g of food |
Hydrosoluble vitamins | |
Vitamin B1 (Thiamine) | Food yeast, cereal bran, cereals, oilseeds, pork |
Vitamin B2 (Riboflavin) | Liver, giblets, eggs, certain cheeses and mushrooms |
Vitamin B3 (Nicotinamide) | Sound of cereals, liver, fatty fish, poultry and other meats |
Vitamin B6 (Pyridoxine) | Dried aromatic herbs, cereal bran, poultry liver and giblets, oilseeds |
Vitamin B7 (Inositol)/Vitamin B8 (Biotin) | Liver, eggs, fish and meat, legumes, mushrooms, sprouted seeds |
Vitamin B9 (Folic acid) | Liver, food yeast, legumes, oilseeds, germinated seeds, giblets, spinach, dried aromatic herbs |
Vitamin B12 (Cobalamine) | Liver, gut, shellfish, fatty fish and other fish |
Vitamin C (Ascorbic acid) | Raw food: guava, blackcurrant, parsley, pepper, lemon, cabbage, kiwi, citrus fruit |
Fat-soluble vitamins | |
Vitamin A (Retinol) | Dried aromatic herbs, liver, tuna, dried mushrooms Foods rich in provitamin A carotenoids (beta-carotene): carrots, sweet potato, spinach, squash |
Vitamin D (Calciferol) | Cod liver oil, cod liver, fatty fish, fish eggs and some margarines |
Vitamin E (Tocopherol) | Wheat germ oil and other vegetable oils, oilseeds |
Vitamin K (K1: Phylloquinone and K2: Menaquinone) | Vitamin K1: dried aromatic herbs, cabbage, spinach, salads. Vitamin K2: liver, butter, poultry, yoghurts |
*The nutritional composition of foods can be consulted on the site of the ANSES, National Agency for Food, Environmental and Occupational Health Safety.
Vitamins do not all come from the same foods, it is therefore necessary to have a varied consumption (foods from different major food groups) but also a diversified diet (foods from the same food group). Micronutrients have no energy value (basically, they do not intervene directly on our energy balance, neither to lose weight nor to gain weight!) compared to macronutrients, which have a direct and significant impact (carbohydrates, lipids and proteins). The ESFA (European Food Safety Authority) has established Nutrient Reference Values (NRVs, formerly known as RDAs: Daily Reference Intakes) for the vitamins summarised in the table below :
Vitamins | Adult NRV Quantity per day |
Vitamin B1 (Thiamine) | 0,1 mg / consumed energy For individual at 2200 Kcak/d = 0.91 mg |
Vitamin B2 (Riboflavin) | 1,6 mg |
Vitamin B3 (Nicotinamide) | 1,6 mg / consumed energy For individual at 2200 Kcak/d= 14.6 mg |
Vitamie B5 (Pantothenic acid) | 5 mg |
Vitamin B6 (Pyridoxine) | 1.7 mg (Men) 1.6 mg (Women) |
Vitamin B8 (Biotin) | 40 μg |
Vitamin B9 (Folic Acid) | 330 μg (in dietary folate*) |
Vitamin B12 (Cobalamine) | 4 μg |
Vitamin C (Ascorbic acid) | 110 mg (Men) 95 mg (Women) |
Vitamin A (Retinol) | 750 μg |
Vitamin D (Calciferol) | 15 μg (600 UI) |
Vitamin E (Tocopherol) | 13 mg (Men) 90 mg (Women) |
Vitamin K (Phylloquinone) | 70 μg |
*Dietary folate is less well assimilated than folic acid.
On the other hand, these NRVs, and therefore the needs, evolve according to certain specific physiological situations, particularly in pregnant or breastfeeding women and the elderly. During pregnancy, the need for vitamin B12 (increasing from 4 to 4.5 μg per day) and folate (increasing from 330 to 600 μg per day) is increased. During breastfeeding, the need for vitamin A (from 750 to 1300 μg per day) and vitamin C (from 95 to 155 mg per day) is also increased. These data suggest the importance of the pre-conceptional period, when optimal nutritional status would help to ensure "reserves" of micronutrients for the periods of pregnancy and breastfeeding, which are critical for the future health of the newborn. Finally, the elderly are more exposed to nutritional deficits due to a decrease and changes in micronutrient absorption [2] as well as changes in consumption (reduced appetite, pronounced dietary choices for foods loaded with flavour, etc.). There are other reasons that can generate deficiencies beyond the physiological status in which we find ourselves. Indeed, they can result from simply poor diets or from other types of factors such as absorption defects linked to intestinal pathologies or even to the taking of medication [3].
On the other hand, it is also less obvious to detect our consumption levels of micronutrients because they have varied and less well known origins, making it more difficult to highlight a possible targeted "deficiency" ("I don't eat enough of this food so I don't consume enough of this vitamin").
Finally, the problem is not essentially based on whether our diet is complete (balanced) or not. It is a question of accepting that the human species is a formidable adaptation machine, but that its corollary implies that we are never 100% adapted to a given biotope and therefore to 100% of our intake in the long term. Today, nutraceuticals offer the possibility to meet or even exceed these needs in order to ensure our well-being and health for the future.
Here we give you some keys but above all some essential information to take the right direction in terms of multivitamins, because history repeats itself, there is a wide variety of products on the market. To benefit from the effects of vitamins, you need to be sure that they reach their targets, ideally in an active (= "ready-to-use") form. This is what defines the famous bioavailability, corresponding to the quality that a nutrient has to be able to be absorbed by the intestinal mucosa and to be used efficiently. Several criteria are taken into account to ensure the bioavailability of a compound and in particular its form (specific structure of the molecule). Indeed, some forms are said to be bioactive, i.e. they correspond to the form in which they can be used by the organism, which facilitates the work of assimilation of the latter [8].
How about a concrete example? Let's talk about vitamin B9 (folic acid from dietary folates). Within the Nutri&Co formula, vitamin B9 has been selected in the form of Quatrefolic. The latter corresponds to 5-Methyltetrahydrofolate (5-MTHF) which is a reduced form of folate. Supplementing this bioactive form also makes it possible to obtain a high bioavailability of vitamin B9 by "short-circuiting" the formation of intermediate molecules. In fact, when the body ingests "standard" folic acid, it must transform it 4 times before obtaining the active form such as Quatrefolic®. These successive transformations obviously generate losses, but also random efficacy, with a strong disparity between individuals [9].
The combination of bioactivity and bioavailability makes it possible to provide the Multivitamins with a bioidentical form of vitamin B9.
It is in this approach to effectiveness, and after more than a year of research, that Nutri&Co has systematically chosen vitamins in their bioactive form. .
In addition to vitamins, our formula also combines the presence of magnesium, trace elements (small-sized minerals) and co-factors that complement the action of supporting physiological reactions, while taking great care to eliminate potentially pro-oxidising or "antagonistic" minerals (iron and manganese in particular).Moreover, calcium has also not been included in our Multi, as the current scientific consensus highlights the sufficient dietary intake of calcium in the French population.
An example of a crucial trace element for our body is zinc. It is mainly found in red meats, certain seeds, shiitake mushrooms and shellfish. In moderate deficiencies, disturbances can be observed such as growth retardation, hypogonadism in young adolescents, healing defects, immune system response defects or neurosensory changes [10]. Three capsules of our multi provides 100% of the NRVs in a Gluconate form, perfectly well assimilated and usable by the body.
With regard to iodine, marine products are known to contain the highest concentration. Depending on their importance, possible deficiencies can have consequences at all ages, from the fetus to adulthood, ranging from developmental problems to neurological disorders. Coverage of iodine intake appears to be particularly important in the periconceptional period up to childhood [11]. Iodine supplementation is not systematic and yet iodine seems to have an important position in clinical practices related to specific nutritional recommendations in the periconceptional period [12].
Among the co-factors selected in the Multivitamin, we find in particular :
This combination therefore increases the antioxidant potential of our body [13] by molecules of various origins and normally poorly bioavailable.
Although vitamins and minerals act synergistically and via complex mechanisms, each has physiological roles that can be briefly listed (biological role tables). These major implications in our physiological balance give vitamins and minerals major axes of activity: vitality, tonus, immunity and antioxidant supply. During particular physiological situations such as pregnancy, meeting the needs for certain vitamins (especially vitamins B9 and D) and minerals (zinc and iodine) is crucial. Indeed, beyond the functions of maintaining our physiological balance, micronutrients also play a primordial role in periods of increased development.
Vitamins | Biological roles |
Vitamin B1 (Thiamine) | Supports energy metabolism (cofactor in the conversion of carbohydrates to energy), nerve and muscle functions |
Vitamin B2 (Riboflavin) | Supports energy metabolism (cofactor in the respiratory chain, component of coenzymes), vision and skin |
Vitamin B3 (Nicotinamide) | Supports energy metabolism (respiratory chain cofactor), nerve function and improves lipid profiles and skin health |
Vitamin B5 (Pantothenic acid) | Supports energy metabolism |
Vitamin B6 (Pyridoxine) | Plays a role in the metabolism of amino acids (cofactor of about 100 enzyme reactions) and fatty acids, in red blood cell production, and heart health |
Vitamin B7 (Inositol) / Vitamin B8 (Biotin) | Plays a role in bone and hair health, in the conversion of nutrients to energy, and in the synthesis of lipids, amino acids and glycogen (endogenous carbohydrate reserves in the body) |
Vitamin B9 (Folic acid) | Participates in DNA synthesis (genetic material), cofactors required for methylation reactions, and allows the formation of new cells and supports heart health |
Vitamin B12 (Cobalamin) | Plays a role in heart health, the production of new cells, in the hydrolysis of amino and fatty acids and supports the maintenance of nerve cells, interacts with the metabolism of vitamin B9 |
Vitamin C (Ascorbic acid) | Plays a role in the synthesis of new cells, in the hydrolysis of fatty acids and amino acids, supports the maintenance of nerve cells (synthesis of hormones and neurotransmitters), acts as an antioxidant, plays a role in the immune system, facilitates the absorption of non-heme iron (from plants), allows the recycling of vitamin E |
Vitamin A (Retinol) | Supports vision, skin and bones, immunity and reproduction, acts as an antioxidant |
Vitamin D (Calciferol) | Plays a role in bone metabolism (bone mineralization), maintains calcium and phosphorus levels in the blood to strengthen bones |
Vitamin E (Tocopherol) | Antioxidant regulating oxidation reactions, protects cell membranes and body compounds (lipids, enzymes...) |
Vitamin K (K1 : Phylloquinone and K2: Menaquinones) | Play a role in the coagulation of proteins in the blood and regulates blood calcium |
(Data from [14,15])
Minerals | Biological roles | |
Magnesium | Find all the importance of magnesium in our physiological functions in the science section of ourMagnesium | |
Zinc | Involved in the structure and catalytic activity of many enzymes, plays a role in the function of the immune system, wound healing, protein synthesis, DNA synthesis and cell division, required in the perception of taste and odour, acts as an antioxidant | |
Selenium | Plays a role in immune functions, acts as an antioxidant | |
Iodine | Plays a role as an essential constituent of thyroid hormones, involved in the general process of development and growth |
(Data from [16])
In conclusion, multivitamin supplementation very often raises the notion of "safety". Beyond the quality of the selected nutraceutical ingredients (origin, efficacy...), it is important to take into account the notion of "dose". We must not confuse NRVs (Nutritional Reference Values), which are thresholds below which we are potentially deficient (different NRVs between regulatory values for labelling and values defined by type of population), and MDIs (Maximum Daily Intakes) which represent the limits not to be exceeded in a supplement.
This is why our formula does not contain "supraphysiological" doses, which some people call "megadoses", thus respecting all French MDIs. It has been recognized that, at short and long-term physiological doses, taking multivitamins (of guaranteed quality!) does not present any danger and would even make it possible to limit the differences in micronutrients that grow over time, and potentially permanently, between our needs and what we consume [17]. Multivitamin supplementation could even be an asset in preventing the risk of the appearance and recurrence of long-term cellular degeneration [18].
Publications
One year of developpement
We undertook to develop our latest generation multivitamins in September 2017. It is by reviewing the entire scientific literature that we came across coenzyme forms of vitamins, liposomal magnesium, high absorption chromium or the synergistic effects of carotenoids and bio-flavonoids.
Security analysis (click on it)
On the tangible improvement of health over time thanks to multivitamins
On the high content and high absorption of UltraMag® (liposomal magnesium)
On the high assimilation of Quatrefolic® (Vitamin B9)
On alpha-lipoic acid as a key element in the synthesis of glutathione
The idea that "taking vitamins is useless when you eat a balanced diet" is still very widespread in France. However, several studies of national scope (SU.VI.MAX, etc.) have shown that micronutrient deficits affect the entire population with special mention for pregnant women, adolescents and over 50s. Note also that a recent and very serious study due to its unprecedented scale (more than 14,000 subjects) * has shown a positive impact on the health of people consuming a multivitamin daily for 11 years! Even if a one-off treatment remains meaningful during the winter or during a gestation period, long-term daily prevention remains the line that we defend at NUTRI & CO.
*: Gaziano, JM; Sesso, H.D .; Christen, W.G .; Bubes, V .; Smith, J.P .; MacFadyen, J .; Schvartz, M .; Manson, J.E .; Glynn, R.J .; Buring, J.E. Multivitamins in the Prevention of Cancer in Men: The Physicians ’Health Study II Randomized Controlled Trial. JAMA 2012, 308, 1871, doi: 10.1001 / jama.2012.14641
Most vitamins are not directly usable by the body and must be activated through various stages of processing. Some steps go wrong and lead to an uncertain result. This is for example the case with folic acid (synthetic B9) that the body struggles to metabolize into B9 and whose excess could have an impact on health * Administered in bioactive form, vitamins are such as organization uses them and avoids hazardous processing steps.
*: Kim YI. Folate and Carcinogenesis: Evidence, Mechanisms and Implications. J Nutr Biochem 1999; 10: 66-88. Medline
The fear of overdose arises from the statement "100% of NRVs" found in nutritional tables. Some neophytes are therefore afraid of going beyond the limits by adding a multi-vitamin to their diet. However, we must not confuse VNR (Nutritional Reference Values *), which are thresholds below which we are deficient, and DJM (Maximum Daily Doses) which represent the limits not to be exceeded in a supplement to date, the EU has not yet determined an ADI for vitamins and minerals. They are therefore specific to each State. These French thresholds are defined in the order of May 9, 2006. Note, however, that part of them were canceled (vitamins K, B1, B2, B5, B8 and B12) by the decision of the Council of State of April 27, 2011. Most vitamins therefore have no safe limits. Our formula does not contain "megadoses" and respects all French DJMs. It should be noted, however, that case law very often authorizes these thresholds to be exceeded. This is for example the case for the following vitamins:
- Vit D: 2000UI in case law vs. 1000UI in DJM
- Vit B9: 400mcg vs 200mcg (especially following the arrival of folate like Quatrefolic)
- Vit B6: 4mg vs. 2mg (following the arrival of the coenzyme form P'-5-P)
- Vit C: 250mg against 180mg.
*: formerly AJR (Recommended Daily Allowance).
Most of the vitamins in our formula are in plant form (A, D, E, etc.), but we do not reject molecular chemistry when it provides a real plus. In reality, synthetic does not necessarily mean artificial. Some human-made vitamins are 100% bio-identical to their natural forms and therefore just as effective *. They therefore have content advantages and are free from extraction solvents.
*: natural and synthetic vitamin C have been shown to have exactly the same level of absorption. Carr AC, Bozonet SM, Vissers MCM. A Randomized Cross-Over Pharmacokinetic Bioavailability Study of Synthetic versus Kiwifruit-Derived Vitamin C. Nutrients. 2013.
There are two reasons for the absence of calcium in our formula:
- Contrary to popular belief, it It is very rare to suffer from calcium deficiency. This mineral is indeed found in abundance in our diet. Today, it is rather the deficiencies in vitamins D and K, the two cofactors of calcium, which are rather singled out when we encounter bone problems.
- Calcium supplementation has not yet proven its effectiveness and could even have a negative impact on the cardiovascular sphere. *
*: MJ Bolland, A. Gray, A. Avenell, GD Gamble, IR Reid. Calcium supplements with or without vitamin D and risk of cardiovascular events: Reanalysis of the Limited Access Women's Health Initiative dataset and meta-analysis. BMJ, 2011; 342 (apr19 1)
The routine prescription of iron is not based on tangible clinical results. However, since the publication of an American study in 2011, iron supplementation is no longer unanimous. This study of more than 38,000 women demonstrated a reduction in lifespan in subjects who took the most iron supplements *. Specialists point to the pro-oxidant effect of iron when it is present in too much quantity in the body.
*: Mursu J, Robien K, Harnack LJ, Park K, Jacobs DR Jr. Dietary supplements and mortality rate in older women: the Iowa Women's Health Study. Trainee in ark medicine. 2011 Oct 10; 171 (18): 1625-33
Many studies have investigated the relationship between β-carotene and cancer risk in smokers, but the results remain controversial. Some have found an increased risk, others have not found a positive relationship between β-carotene and cancer risk in smokers. Moreover, any risk must be considered, but it is important to place oneself in the nutritional conditions observed or imposed in these studies. In fact, in the large landmark studies, the β-carotene supplements imposed were 20 mg per day, or even more, and over several years. The EFSA (“European Food Safety Authority”) ruled in 2012, indicating that exposure to β-carotene, at levels below 15 mg per day, did not present any harmful effects on health. in the general population, with specific reference to smokers. By positioning itself in a context of consumption, in France, the national individual study of food consumption (INCA3, 2017) showed in particular that the average daily intake of β-carotene was 2.7 mg. This highlights a notable difference between these intakes and those that can be predicted in the presence of possible supplementation. As part of our Multi, 800 micrograms or 0.8 mg of beta-carotene are present for 3 capsules. In all cases, therefore, we are far below the dose accepted as safe by the EFSA.
A benchmark in nutraceutical processing, ISO 22000 and organic certified.
Lypotec is an international group born in Barcelona specializing in liposomal forms of minerals for the Cosmetics and Nutraceutical industry.
Kappa bio science laboratory.
BTSA Lab
Gnosis implements biotransformation (fermentation) processes to design nutritional assets with the aim of improving human health and well-being.
Isaltis is a French company specializing in the production and study of highly bioavailable minerals.
Plantex is a French SME recognized worldwide for its expertise in plant extraction.
Selenium • Lynside®
Maisons Alfort, France
Laboratoire Lesaffre