Millet & Biotin

When to take Millet & Biotine?

• Millet & Biotine must be taken for breakfast.

How many capsules?

• Children: Not recommended.
• Adolescents: Not recommended.
• Adults: 2 capsules per day.

Duration of a take

• Take a short, medium take.
• Take a 1 to 2 week break every 3 months of taking.

How to take your capsules?

• To be taken with a large glass of water, quite simply.

Duration of a bottle

• The bottle of Millet & Biotine lasts 30 days.

Precautions for use

• Food supplement based on plants and vitamins, to be used in addition to a healthy and balanced diet.
• Do not exceed the recommended daily doses.
• Pregnant or breastfeeding women should seek the advice of a doctor before any supplementation.
• Not recommended for children under the age of 18.
• Not recommended for prolonged use .

Storage conditions

• Store in a dry place away from light and heat.
• Keep out of the reach of children.

For 2 capsules

Organic Shea Butter: 458 mg

Organic Millet Seed Oil ( Keranat® ): 300 mg
including Miliacin: 3 mg

Organic Basil leaf extract: 3 mg
including Biotin: 0.050 mg (100% of AR * )

Vegetable capsule Licaps: 192 mg

* AR: Reference intake

Ingredients: Refined shea almond butter ** Butyrospermum Parkii, Keranat® ** (Millet seed extract ** Panicum miliaceum, wheat seed extract * Triticum vulgare / aestivum , sunflower oil ** Helianthus annuus, rosemary extract ** Rosmarinus officinalis), tunica of plant origin: hydroxypropylmethylcellulose (Licaps®), organic basil leaf extract ** (Ocimum basilicum L).
Licaps® is a registered trademark of Lonza or its subsidiaries.

** ingredients from organic farming

Hair loss concerns us all

Our hair capital is subject to tests throughout our lives :

• The return of seasons such as summer that weakens our hair (sea, sun...).
• After a period of "physical" stress: malnutrition, intense anxiety, surgery...
• When there are major hormonal variations (puberty, menopause, aging, pregnancy).
• And in some cases, after pathologies that cause hair loss.

The mechanisms of hair loss

Hair is alive, and at any moment we find hair at different stages of development :

• growing (80% of hair at this stage)
• stable (1% of hair at this stage)

• It is therefore completely normal to lose hair on a daily basis. Generally, more than 100 hairs lost per day is called alopecia, i.e. a loss that is too important and therefore causes a visible decrease in hair density.

  According to a survey IFOP, 3 out of 4 French people who do not suffer from baldness declare that they are confronted with a significant loss of hair. Women are particularly prone to this phenomenon [1].

  The hair cycle

  In addition to anti-hair loss treatments or cosmetic care, it is now possible to take care of your hair with nutricosmetics. And to understand how to act, we must first go back to the natural hair cycle, because that's where it all comes down to [2,3].
  
  i. Hair growth, Anagen phase
  This is the crucial phase, it lasts 2 to 6 years. Normal hair is 85% anagen hair, i.e. in the "growing" phase. Today it is strongly affected by stress and pollution. In the presence of pollution particles, a significant decrease in the beta-catenin protein, responsible for hair growth, is detected. Results ? A weakened anagen phase, dull and less dense hair, and significant hair loss [4]. Indeed, it is from the very beginning of this phase that hair growth is activated and that the hair becomes anchored in its follicle. The follicle is therefore a strategic and key place in the health of the hair.

  Viewing the length of this stage, it is easy to understand that a weakening can have a dramatic effect on the health and appearance of the hair, as it will take several years before a "new generation" of growth is achieved.
  
  ii. Hair maintenance, Catagen phase
  Surprisingly, this is the shortest phase of the cycle, since it lasts only 3 weeks on average. Logically, only 1% of the hair is in this phase. During these three weeks, the hair must be stable and strengthened - so that it does not move too quickly into the telogen phase (hair loss).
   
  iii. Hair loss, Telogen phase
  This phase lasts 3 to 4 months and is inevitable. It concerns a maximum of 15% of a normal hair. At the end of this phase, the hair falls out, leaving the place to the hair follicle reactivated in the anagen phase. This is the beginning of a new cycle and therefore of a new hair. In normal hair, we lose 50 to 100 hairs per day. A more important hair loss can be a sign of a problem.
  
  To act on the hair growth cycle, the ideal is to aim at the anagen phase, since it is there that the hair is formed and everything is at stake. Nutraceuticals offer precisely the possibility to do just that, thanks to certain ingredients that have proven themselves in clinical trials.

  The Keranat®: at last a vegetal AND effective approach thanks to millet!

  The originality of Keranat® compared to first generation solutions, such as keratin or cysteine, is that it acts on the two crucial phases of the hair cycle: growth and maintenance. In other words, rather than relying entirely on structure (keratin and its precursors such as cysteine), Keranat® provides the foundation: hair growth and its foundations. Moreover, keratin suffers from low bioavailability and is of exclusively animal origin. Whereas millet is bioavailable and 100% vegetable, organic and vegan.

  2 clinical studies using Keranat®

  Keranat® has been the subject of two well-conducted clinical studies [5,6]. 5,6] They were carried out on a total of 120 women who noted clear positive effects on their hair. The clinical tests carried out on these women demonstrated the millet-hair link:

  • A reduction in hair loss,
  • An activation of their hair growth,
  • And an improvement in the beauty and shine of their hair.

  Miliacin, the key molecule of Keranat®

  Miliacin from millet is the main molecule that gives Keranat® its activity. Clinical data have shown that it is beneficial in maintaining the natural hair cycle by reinforcing the anagen (growth) phase. In particular, it has been shown to increase the production of growth factors such as IGF1 and therefore of cell proliferation at the level of the hair follicle bulb. These extremely interesting results have been associated with an increase in the thickness of collagen (structural fiber of our body) in the bulb. The results of these trials suggest a real positive effect of Keranat® on hair growth and a better anchoring of the hair at its base.

  Vectorized miliacin, 6 times more effective

  The encapsulation technology patented by our partner Robertet allows our miliacin to have a better bioavailability and therefore a better efficacy. Miliacin is encapsulated in polar lipids extracted from wheat, which also have a function, since they boost the production of collagen, a major constituent of the hair sheath. The hair is thus strengthened during the catagen phase (maintenance).

  The first vegetable biotin bio

  Biotin, known as the hair vitamin, is now offered exclusively in a synthetic form. We have succeeded in finding this vitamin in a natural and organic form, extracted from Basil leaves.

  Publications

  1. Tosti, A.; Piraccini, B.M.; Iorizzo, M.; Voudouris, S. The natural history of androgenetic alopecia Blackwell Publishing,Ltd. J. Cosmet. Dermatol. 2005, 3.
  2. Alonso, L.; Fuchs, E. The hair cycle. J. Cell Sci. 2006, 119, 391–393, doi:10.1242/jcs.02793.
  3. Blume-Peytavi, U.; Tosti, A.; Whithing, D.A.; Trüeb, R. Hair Growth and Disorders; Springer.; 2008; ISBN 978-3-540-46908-7.
  4. Sadick, N.S.; Callender, V.D.; Kircik, L.H.; Kogan, S. New Insight Into the Pathophysiology of Hair Loss Trigger a Paradigm Shift in the Treatment Approach. 2017, 16, 6.
  5. Boisnic, S.; Branchet, M.; Gaillard, E.; Lamour, I. Miliacin Associated with Polar Lipids: Effect on Growth Factors Excretion and Extracellular Matrix of the Dermal Papilla Hair Follicle Model Maintained in Survival Conditions. Hair Ther. Transplant. 2016, 06, doi:10.4172/2167-0951.1000143.
  6. Keophiphath, M.; Courbière, C.; Manzato, L.; Lamour, I.; Gaillard, E. “Miliacin encapsulated by polar lipids stimulates cell proliferation in hair bulb and improves telogen effluvium in women.” J. Cosmet. Dermatol. 2020, 19, 485–493, doi:10.1111/jocd.12998.

Analysis results:

• Pesticides and Fungicide Analysis Report